We surmise that results obtained from the experiments described in this section cannot serve to understand the role of INaL in arrhythmogenesis.
step one. Van Driessche W, Lindemann B: Concentration dependency away from currents as a result of solitary salt-selective pores inside frog facial skin. Nature. 1979; 282 (5738): 519-520 PubMed Abstract | Blogger Complete Text message
It means the newest https://essayrevisor.com/essay-writing-service-usa/ solid results submit from this manuscript is actually maybe not rationalized and i try not to accept this new manuscript within this function
Brand new article authors has explained a number of the concerns I elevated within the my prior opinion. Regrettably, the big difficulties have not been treated by this inform. Once i manufactured in my personal earlier comment, We consider it unlikely that every those individuals circumstances are fixed only because of the several extra sentences. Instead there are still certain fundamental concerns to your fresh structure and you will, extremely vitally, with the analysis.
This means the brand new good results put forward through this manuscript is actually perhaps not rationalized and that i usually do not approve this new manuscript within form
The brand new experts has made clear a number of the concerns I elevated from inside the my earlier feedback. Unfortunately, all big dilemmas have not been handled through this revise. While i stated in my earlier remark, We deem it impractical that most men and women circumstances are fixed just by a number of additional paragraphs. Instead there are still certain standard concerns on the experimental structure and you can, really vitally, to your data.
- Top issue is when I adopted brand new description of the ways in the last variation it was you are able to to decode, that have nearly primary reliability, any arbitrary stimulus brands I selected. Discover to have samples of that it reanalysis. Regardless of whether i imagine your real stimuli looked during the an after time otherwise try consistently changing anywhere between code and you will silence, the new decoding is always near to primary. This is certainly a sign your decoding has nothing to-do toward real stimuli heard of the Transmitter but is opportunistically exploiting other has actually about investigation. The brand new control research the writers performed, treating the brand new stimulus names, don’t target this dilemma whilst suffers from equivalent situation. Fundamentally, just what classifier is actually presumably using it’s time that has introduced since tape come.
- The cause of this will be allegedly the people put low-independent data having knowledge and you will evaluation. While I’m sure correctly (pick area step 3), random testing half of information products away from an enthusiastic EEG shadow aren’t separate data. Repeating the analysis five times – the manage analysis the new article writers did – isn’t a sufficient way to target which question. At random looking for samples out-of a time collection that has slow alter (such as the sluggish wave interest that presumably reigns over these tracks significantly less than these situations) commonly usually incorporate strong temporal correlations. Get a hold of TemporalCorrelations.jpg set for 2D density histograms and you can a correlation matrix appearing it.
- Just like the modified actions part will bring greater detail today, it continues to be confused about what data were used. Antique classification data declaration exactly what studies has actually (typical columns from the study matrix) and you may what findings (usual rows) were utilized. Something might possibly be an element but normally it is brand new different EEG channels or fMRI voxels an such like. Findings are big date points. Right here I suppose the latest article authors turned brand new raw examples into the a great some other area playing with principal parts data. It is not stated when your dimensionality is actually shorter utilising the eigenvalues. Either way, I suppose the information and knowledge products (collected at the 128 Hz) were next used while the observations together with EEG avenues turned by PCA were utilized while the has actually. The fresh new stimulus labels was basically tasked as the With the otherwise Of per decide to try. Some fifty% off examples (and you may brands) was then chose randomly getting knowledge, and also the other people was used to have review. So is this right?
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